Let’s explore stem cells, peptides and a patch that uses light. By the end, you will hopefully understand and appreciate why we promote said patch. The short of it: The X39 patch recycles the body’s infrared light to activate stem cells by elevating copper peptide (GHK-Cu), leading to fast and often miraculous improvements.

I know, it sounds too good to be true. Trust me, I was super sceptical as well. Now I am an avid supporter for many reasons:

1. It is super easy and only costs the price of a cup of coffee per day
2. Since it is so easy, adherence is very high
3. People feel and do better right away
4. It works via light and the body’s natural pathways
5. It is the easiest way of getting more light into the body for those unable or unwilling to get more sun in their eyes and onto their skin
6. No substance is applied, introduced or injected
7. It gives people a big win and, thus, a better foundation to implement the essential lifestyle changes necessary

Many of us live in a city, are stuck in an indoor job, live at a high latitude with little sunlight, are burdened by disease or simply have very little time to spare. This can make seeing the sunrise, spending more time outside, moving more, grounding, minimizing artificial EMFs, etc, difficult or impossible.

A jump start that helps improve people’s health and vitality would come in handy. With that boost of well-being and extra energy, making significant lifestyle changes becomes more manageable. This is where the magic of the X39 patch comes in. To elevate us wherever we are, to restore capacity and empower us to move forward more effectively.

How is all this possible? Stem cells, peptides and light. We won’t dive into the light aspect here, but please read our app’s learn sections on light/dark, artificial light and red/infrared light for a deep dive.

Stem Cells

Stem cells are the body’s raw materials — cells from which all other cells with specialized functions are generated. Under the right conditions, stem cells divide to form more daughter cells. These daughter cells become either new stem cells or specialized cells (differentiation) with a more specific function, such as blood cells, brain cells, heart muscle cells or bone cells. Stem cells can regenerate and repair tissues that have been damaged or affected by disease. 

As stem cells age, their renewal ability deteriorates, and their ability to differentiate into various cell types is altered [1]. While our need for stem cells increases as we age (due to more damage and inflammation), fewer and fewer of them are released into our bloodstream. With increasing age, the circulating stem cells drop dramatically. The fewer stem cells we have and the less active they are, the longer it takes to repair damage and less damage can be taken care of [2]. Thats why it takes longer to heal a wound or recover the older we are. 

It is also important to note that modern technology’s non-native electromagnetic fields (EMFs) deplete stem cells [3, 4, 5]. Since EMF pollution is ubiquitous and increases exponentially, this speeds up ageing.

This makes it even more important that we increase stem cell activation to be able to ward off inflammation and damage. How can we naturally increase stem cell activation? Exercise, sleep, fasting, and elevating a specific peptide [6, 7, 8, 9, 10, 11].

Peptides

Peptides are smaller versions of proteins. Both proteins and peptides are made up of amino acids, but peptides contain far fewer amino acids than proteins. Bioactive peptides can have anti-ageing, anti-inflammatory, or muscle-building properties.

The peptide GHK (glycyl-L-histidyl-L-lysine) is seen as an anti-ageing molecule [12]. GHK is a naturally occurring, nontoxic peptide found in plasma, saliva, and urine and is used for wound treatment and skin care [13]. It loves to bond with copper (Cu), regulating its metabolism and improving its bioavailability [14]. GHK-Cu accelerates the process of regeneration, wound healing, and antioxidant and anti-inflammatory actions [15, 16]. GHK has also been found to possess powerful cell protective actions, such as multiple anti-cancer activities, anti-anxiety, anti-pain, DNA repair & more [17].

GHK has been found to reset genes to a more healthy state [18] and improve stem cell activity [19, 20, 21]. Powerful stuff, alright. But what does this have to do with a patch you put on your skin?

Well, it has been demonstrated that wearing the X39 patch increases GHK-Cu levels significantly [22].

What are people experiencing?

Who should try the X39 patch?

Stem cell production declines with age and with chronic disease. Hence you can expect increasing benefits the older and sicker you are. That being said, many people in their 20s and 30s use the X39 patch to improve energy levels and sports performance and recovery.

People who are copper toxic will benefit hugely. While copper is an essential trace element, excess copper in the bloodstream can create symptoms such as fatigue, nausea, depression, irritability, cravings, mood swings, and brain fog, among many others. Long use of birth control pills or copper IUDs (intrauterine devices) often leads to copper toxicity. High-free copper levels in the blood are also seen in Alzheimer’s and Parkinson’s, while brain copper levels are too low in these diseases [23, 24, 25].

The excess copper is bound by elevated levels of the peptide GHK, which the X39 patch increases [22]. Instead of creating damage, the free copper is bound to form GHK-Cu and thus turned into a powerful anti-ageing ally [12].

If you had surgery, heart attacks, have wounds that need to heal or are dealing with pain or skin issues, try these patches due to the increase in wound healing and collagen production. The more time you spend inside and are bombarded by EMFs, it is also a good idea to use these patches as a mitigation strategy. 

Experience it yourself with zero risk!

Lifewave has a money-back guarantee on your first order. That means you can order the X39, experience how you feel and decide if you are happy or not. In case it doesn’t move the needle for you, get your money back hassle-free.

If you want to dive deeper into the X39, you can learn more here: startx39.com

To order, click here. And make sure to purchase as a preferred customer or sign up to Lifewave to claim wholesale pricing! And please let us know your experience by dropping us an email to support@circadian.life.

References

[1] Urbán, Noelia, and Tom H Cheung. “Stem cell quiescence: the challenging path to activation.” Development (Cambridge, England) vol. 148,3 dev165084. 8 Feb. 2021, doi:10.1242/dev.165084

[2] Paul Knoepfler, “How many stem cells do we have & can you run out?”, 26 January 2022, The Niche – Truisted stem cell blog and resources, https://ipscell.com/2022/01/how-many-stem-cells-do-we-have-can-you-run-out/

[3] Shahbazi-Gahrouei, D et al. “Effects of RF-EMF Exposure from GSM Mobile Phones on Proliferation Rate of Human Adipose-derived Stem Cells: An In-vitro Study.” Journal of biomedical physics & engineering vol. 6,4 243-252. 1 Dec. 2016, PMID:28144594

[4] Daryoush Shahbazi-Gahrouei et al. “Exposure to global system for mobile communication 900 mhz cellular phone radiofrequency alters growth, proliferation and morphology of michigan cancer foundation-7 cells and mesenchymal stem cells.” International Journal of Preventative Medicine. Vol 9. 2018. Issue 1, doi:10.4103/ijpvm.ijpvm_75_17

[5] Yu, Chan-Wei et al. “Nanoplastics exposure disrupts circadian rhythm associated with dysfunction of the endolysosomal pathway and autophagy in Caenorhabditis elegans.” Journal of hazardous materials vol. 452 (2023): 131308. doi:10.1016/j.jhazmat.2023.131308

[6] Wahl P, Brixius K, Bloch W. Exercise-induced stem cell activation and its implication for cardiovascular and skeletal muscle regeneration. Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy. 2008 ;17(2):91-99. doi:10.1080/13645700801969816

[7] Liu, Ling et al. “Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging.” Cell stem cell vol. 30,5 (2023): 689-705.e4. doi:10.1016/j.stem.2023.03.016

[8] Fukada, So-Ichiro, and Ayasa Nakamura. “Exercise/Resistance Training and Muscle Stem Cells.” Endocrinology and metabolism (Seoul, Korea) vol. 36,4 (2021): 737-744. doi:10.3803/EnM.2021.401

[9] Elkhenany, Hoda et al. “Tissue regeneration: Impact of sleep on stem cell regenerative capacity.” Life sciences vol. 214 (2018): 51-61. doi:10.1016/j.lfs.2018.10.057

[10] Cheng, Chia-Wei et al. “Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression.” Cell stem cell vol. 14,6 (2014): 810-23. doi:10.1016/j.stem.2014.04.014

[11] Cheng, Chia-Wei et al. “Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet.” Cell vol. 178,5 (2019): 1115-1131.e15. doi:10.1016/j.cell.2019.07.048

[12] Dou, Yan et al. “The potential of GHK as an anti-aging peptide.” Aging pathobiology and therapeutics vol. 2,1 (2020): 58-61. doi:10.31491/apt.2020.03.014

[13] Pickart, Loren et al. “GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration.” BioMed research international vol. 2015 (2015): 648108. doi:10.1155/2015/648108

[14] Park, Jeong-Ran et al. “The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice.” Oncotarget vol. 7,36 (2016): 58405-58417. doi:10.18632/oncotarget.11168

[15] Pickart, Loren et al. “The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health.” Oxidative medicine and cellular longevity vol. 2012 (2012): 324832. doi:10.1155/2012/324832

[16] Pickart, Loren. “The human tri-peptide GHK and tissue remodeling.” Journal of biomaterials science. Polymer edition vol. 19,8 (2008): 969-88. doi:10.1163/156856208784909435

[17] Pickart, Loren, and Anna Margolina. “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.” International journal of molecular sciences vol. 19,7 1987. 7 Jul. 2018, doi:10.3390/ijms19071987

[18] Pickart, Loren et al. “GHK and DNA: resetting the human genome to health.” BioMed research international vol. 2014 (2014): 151479. doi:10.1155/2014/151479

[19] Pickart L, Margolina A. The Effect of the Human Plasma Molecule GHK-Cu on Stem Cell Actions and Expression of Relevant Genes. OBM Geriatrics 2018;2(3):009; doi:10.21926/obm.geriatr.1803009

[20] Kang, Youn-A et al. “Copper-GHK increases integrin expression and p63 positivity by keratinocytes.” Archives of dermatological research vol. 301,4 (2009): 301-6. doi:10.1007/s00403-009-0942-x

[21] Choi, Hye-Ryung et al. “Stem cell recovering effect of copper-free GHK in skin.” Journal of peptide science : an official publication of the European Peptide Society vol. 18,11 (2012): 685-90. doi:10.1002/psc.2455

[22] Connor CA, Connor MH, Yue D, Eickhoff J, Wagner S, et al. (2021). “Double-Blind Testing of the Lifewave X39 Patch to Determine GHK-Cu Production Levels.” Internal Med Res Open Journal. Volume 6(1): 1-3. link

[23] Jingshu Xu and others, Evidence for widespread, severe brain copper deficiency in Alzheimer’s dementia, Metallomics, Volume 9, Issue 8, August 2017, Pages 1106–1119, doi:10.1039/c7mt00074j

[24] Rozzini, Luca et al. “Serum Non-Ceruloplasmin Non-Albumin Copper Elevation in Mild Cognitive Impairment and Dementia due to Alzheimer’s Disease: A Case Control Study.” Journal of Alzheimer’s disease : JAD vol. 61,3 (2018): 907-912. doi:10.3233/JAD-170552

[25] Squitti, Rosanna et al. “Free copper distinguishes mild cognitive impairment subjects from healthy elderly individuals.” Journal of Alzheimer’s disease : JAD vol. 23,2 (2011): 239-48. doi:10.3233/JAD-2010-101098